Congratulations Regeneron Science Talent Search Top 300 Scholars: Sophie G. & Logan R

Sophie G. and Logan R. have been named as top 300 scholars in the Regeneron Science Talent Search 2024, the nation’s oldest and most prestigious science and math competition for high school seniors.  The Regeneron Science Talent Search scholars were selected from 2,162 applications received from 712 high schools across 46 states, Guam, Puerto Rico and ten other countries. Scholars were chosen based on their exceptional research skills, commitment to academics, innovative thinking and promise as scientists and hail from 196 American and international high schools and homeschools in 36 states and China.

 

Sophie's project uses a fruit fly model to characterize how a novel cancer drug, MRTX1133, behaves in the body, and suggests mechanisms of resistance to the drug. This is the first time fruit flies have been used to model the effects of a drug like MRTX1133, which is among the first of its kind to effectively treat a cancer mutation that, up until a few years ago, was considered “undruggable.” 

 

Logan's research investigates the most massive and luminous phenomena in the entire universe, supermassive black holes at the centers of galaxies, known as Active Galactic Nuclei (AGN). Specifically, I investigated the AGN in galaxy NGC 4151, a relatively nearby galaxy, testing to see if its behavior was consistent with the new, controversial theory of AGN, the unified model.

Congratulations to Sophie and Logan with appreciation for the efforts of the HCHS Science Department and the faculty advisors of the research program, Mr. Brian Park, Ms. Christina Gonzalez and Mr. Cheng, under the leadership of Science Department Chair, Dr. Phil Jeffery.